Daily Diet Blog

May 16, 2008

Diet Pill May Hinder Brain Development in Young

Filed under: Prescription Diet Aids — EatingToLive @ 7:18 am

The latest blockbuster diet drug that actually went bust in the US and is only sold now in Europe, Rimonabant, otherwise known as Acomplia, has been pegged as having an effect on young mice who were studied in the lab (poor mice!) as having an effect on normal brain development during growth phases. 

It was shown to inhibit their adaptability, so that the brain could not learn to adapt to certain situations as the individual mouse grew, as a normal youth would be able to.  This is just another blow to the drug, although they never indicated that it should be used in children, and it is actually not even allowed to be prescribed for children currently where it is approved for use. 

The drug works by suppressing the appetite by way of hindering the same chemical process by which people who smoke marijuana get hungry in the brain.  However, the reason that the drug was not approved in the US is that it was demonstrated to cause some forms of psychiatric problems in the patients that it was given to in controlled studies - to the effect of 40%, which is of course totally unacceptable. 

Most alarmingly was the reports of suicidal thoughts that accompanied the use of the drug, and this was unacceptable for the FDA to approve the drug.  Just another reason to give a good herbal weight loss pills a try, right?  It seems like a lot of these blockbuster pharmaceutical weight loss drugs just cause more problems than they’re worth, way more than outweighing (no pun intended) the health risks that excess weight brings. 

Acomplia is set to come back out as a treatment for type II diabetes in 2009, but it is unclear whether they are trying to reformulate the product at all to make it safer for human consumption and reduce the potentially life threatening side effects of suicidal thoughts. 

 

November 23, 2007

Acomplia Now Also Linked to Anxiety, Depression

Filed under: Prescription Diet Aids — EatingToLive @ 1:44 pm

One of the newer weight loss drugs has some more bad news unfortunately for those that are overweight and hopeful that this diet product would be the answer to their weight and diet woes.  Before we reported that word on the “street” was that Acomplia was linked to it’s patients having suicidal thoughts, although in a statistically rather small portion of the patients. 

Now, new evidence is showing that patients taking the Acomplia diet drug are showing a doubling in the tendency toward anxiety and depression, which is not good news, especially considering that anxiety and depression are just as bad if not worse than having excess weight, so now patients must decide if the risk is worth the payoff (hopefully substantial weight loss).  Makes natural appetite suppressants pretty appealing, huh?

The study focused on patients taking the drug, and found that patients that were taking 20 milligrams or more of the diet and weightloss product were more than two times likely to stop treatment on the drug due to depression and anxiety cropping up to the point that it seemed unbearable.  This follows an advisory by a panel to not approve the diet drug after findings that it increased suicidal thoughts. 

July 19, 2007

Alli’s Selling Like Hotcakes!

Filed under: Prescription Diet Aids — EatingToLive @ 7:00 pm

The new over the counter version of the formerly only prescription diet pill called Xenical, Alli, has been selling better than the make of the diet pill had assumed, even thought the consequences of cheating on your diet while on Alli may be disastrous and more than just a little embarrassing. 

What I mean by this is that people are noting that part of their success on the diet pill is due to the fact they when they cheat, they pay with runny still and sometimes uncontrollable bowel movements.  The diet pill make even suggests that you try the drug first on a day off just in case you experience the side effect of loose stool or uncontrolled bowel movements, or taking a change of underwear and pants, or wearing darkly colored pants until you get used to it. 

Is it me, or does this seem like overkill?  Alli is supposed to block approximately 25% of the fat the enters your body in any given meal.  It does this by eliminating that fat through your stool, so logically, if you cheat and eat a fatty meal, you will have a big mess on your hands, your couch, or whatever you happen to be sitting or laying on at the time your body decides to expel the extra fat from having Alli in it. 

Health and fitness supplements for fat loss like herbal phentermine and others that help control the appetite like Hoodia gums and other hoodia products I think would be more the way to go.  I don’t know about you, but I would not like the idea that I could possibly lose control of my bowels if I even ate a little too much fat in my diet one day.  This could be extremely embarrassing. 

Some are looking at it as almost a training and reward type of learned behavior, since people tend to stay away from fat due to the new consequences the Alli diet pill may unleash, and that’s fine if it works for them, but I think there are healthier ways to go about losing weight.  Is anyone else also concerned about what a pill that can alter your elimination process like this could possibly do to your bowels long term?  Yikes…. 

June 25, 2007

Does Diet Drug Alli Have a Fatal Side Effect?

Filed under: Prescription Diet Aids — EatingToLive @ 12:45 pm

The diet drug Alli, which is causing the latest weight loss medication sensation in the news lately, is the nonprescription form of the prescription weight loss drug Xenical, which has been sold for some time under the name and has been rebirthed as a nonprescription strength drug that can help you lose weight. 

But the side effects most notoriously tied to Alli and Xenical are that you may suffer runny stools since it does not allow full absorption of fats, and also unpleasant gas and gastric pain.  Yeah, these are really unpleasant and embarrassing side effects, but are they actually harmful?  Well, one group does think so, and even goes so far as to say that Alli is linked to colon cancer, which can be a fatal disease as we all know. 

The consumer advocacy group claims that clinical trials on mice show that the diet drug had caused precancerous lesions in the colon.  They say that the FDA should have never approved the drug for over the counter use because there are really no studies that prove that over the long term this will not cause the same in humans that consume the diet drug. 

The drug actually expels excess fat consumed by the person who is taking the drug and that is the reason for the runny stool, because the excess fat has to go somewhere.  I remember the same side effect occurred with the Olestra fake fat that was on the market for a while, and I remember some pretty unpleasant side effects from that as well, it just didn’t feel natural, like you were sort of playing a dangerous game with your colon and digestive system by eating foods that are supposed to be absorbed by the body and are instead expelled through an unnatural process.  I would say a carb blocker would be a safer way to go if you’re concerned about losing weight and want to expel excess carbs from your body instead of fat. 

June 16, 2007

Acomplia Gets Rejected

Filed under: Prescription Diet Aids — EatingToLive @ 1:08 pm

The newer weight loss pill (prescription) that goes by the brand name of Acomplia but it’s drug name is Rimonabant, has been unanimously rejected for approval for use in the US by the panel the FDA uses to try to decide whether or not they want to approve a certain drug for sale and use here in the US.  Although the FDA is not required to follow the advisory panel’s advice, it usually does, and in this case since the decision was unanimous that the panel’s participants didn’t like what they heard, the FDA rejected the drug for sale in the US.

The reason for the unanimous decision was that the drug was shown to almost double the risk of suicidal thoughts, depression, anxiety and sleeplessness in it’s subjects.  Since the side effects are real and possible, the drug company recommende the way around such dangers was to screen potential patients of the drug for depression and anxiety prior to prescribing it.

The advisory panel decided this was not good enough though, and the potential for this serious side effect sounded too dangerous to allow for widespread sale here in the US. 

The bigger problem was that most of the patients who reported the mental problems while on the drug had absolutely no history of depression or related mental health issues.  Since the studies were done with half placebo and half on the drug, the findings were really significant, since these patients with no history of mental illness reported the issues. 

The weight loss pill has been shown to be effective for weight loss though, but the findings suggest that much more research on the drug’s effect on the mind is needed before the FDA can conscienably approve a drug that can have a significant effect on one’s psyche. 

January 20, 2007

Appetite Control Gum to Be Approved Soon?

Filed under: Prescription Diet Aids — EatingToLive @ 2:51 pm

The latest news in the never-ending world of weight loss and dieting aids, is the latest diet aid may be a chewing gum which helps the brain register fullness sooner than it normally would.

This earlier fullness or satiety, would, of course, result in weight loss for the patient since they would be eating smaller amount of food and taking in less calories, many times substantially less, depending on the depth of the level of appetite control achieved.

Calorie intake and portion control are two of the leading reasons Americans are currently suffering astronomical percentages of obesity and weight related health issues today.

Unfortunately, I did not get to see what the active ingredient in this new chewing gum would be, since my internet decided to time out on me halfway through my reading and I couldn’t locate the article again, but it is clearly something that either controls the blood sugar which can in turn control the appetite, or it may also control the brain area responsible for the appetite and the process of feeling “full”.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

January 10, 2007

Breakthrough Weight Loss Drug Approved by FDA…For Dogs

Filed under: Prescription Diet Aids, Diet and Weightloss News — EatingToLive @ 11:23 am

When I first saw the headline when checking my Yahoo mail account, I got excited, because we all know that new and exciting medical weight loss drugs, let along herbal weight loss pills, come only every once in a blue moon usually, especially ones that cause any type of stir or have any real merit. Well, come to think of it, most of them end up being unsafe in some way, but nonetheless, I was still kind of excited to read about the newest weight loss pill approved by the FDA. Then I read the rest of the headline, and it’s actually and FDA approved weight loss drug for Dogs.

Yep, that’s right, our good old FDA approved a diet pill for our pooches who are carrying around a little too many pooch pounds on their bellies and their hind quarters. The pill is called Slentrol, and it is approved only for use on dogs who are actually categorized as “obese”. What this means is that they must be considered to be at high risk for certain diseases and health disorders because of their high weight, to be put on this obesity prevention and weight reduction pill expressly for canines. The liquid drug, by the drug giant Pfizer, is a drug which is supposed to limit the amount of fat a dog’s body can absorb.

Ooh, wait a second, wasn’t that what the nasty fat substitute, Olean was supposed to do for humans? Remember the horrible gastrointestinal side effects? I hope these poor guys don’t have to go through that misery simply to get slimmer. How about these owners just put their dogs on a restricted diet?

January 1, 2007

Excalia Weight Loss Drug to Use Nausea as Appetite Suppressant?

Filed under: Prescription Diet Aids — EatingToLive @ 6:38 am

I saw an interesting segment on Foxnews about a diet drug that is currenlty in it’s beginning testing phases (which means it’s a LONG time til market), called Excalia.  While some are saying this diet drug could be the “miracle weight loss pill”, the methods by which this pill are hypothesized to work are not exactly desirable to say the least. 

The Excalia drug, who’se developing drug company is set to offer an IPO for their stock to get the word out about this revolutionary diet product, works on the premise that it tricks the brain into not eating since it makes the subject feel nauseous and full.  I don’t know about you, but would you want to feel nauseous and even possibly be throwing up, simply to lose weight?  They said the pill Excalia has only been tested on about 100 subjects so far with good weight loss results, but this is far from done being tested for safety. 

December 20, 2006

Phentermine : What is It?

Filed under: Prescription Diet Aids — EatingToLive @ 6:30 pm

Phentermine is a pharmaceutical weight loss drug that gained recognition, both good and bad, when it was part of the duo Phen Fen, which eventually was banned from the pharamceutical market place after people who were using the pharmaceutical combo drug had very serious side effects, even resulting in death in some cases. 

Phentermine, the prescription kind, is an appetite suppressant in potent form.  While it is true that many people have lost a lot of weight on phentermine, it is not without its side effects and downsides.  The  manufacturers of phentermine are cautious to say that their diet product will help you, but you must also watch what you eat and exercise, so it is by no means looked at my consumers as a “miracle weight loss pill” where you do not have to do any work.

Phentermine is only approved for the short term treatment of obesity and weight loss, which means patients can only be put on phentermine by a physician for a maximum of about anywhere for 6-12 weeks, depending on the patient.

The drug is primarily known to suppress the appetite, but the downside to many drugs that do this is that they significantly elevate the heart rate in some cases, which can lead to problems, like dizziness, dry mouth, blurred vision and other side effects that are often related to taking this type of product which can kind of “speed” the whole system up. 

This is exactly why phentermine is probably only FDA approved for short term use, because long term use may very well damage the system or possibly even organs (no long term study has been done though, because phentermine is only approved for short term use for obesity). 

If you’re looking for a safe alternative to phentermine, there are herbal phentermines out there that accomplish the same appetite suppression, without the side effects and danger of a hard pharmaceutical drug. 

See herbal phentermine review for more information on one such supplement which curbs appetite.  It’s the perfect thing to get you back on track after getting far off track (like I often do) from the holiday binge season! 

December 2, 2006

Clenbuterol : Miracle Weight Loss or Dangerous Drug?

Filed under: Weight Loss, Prescription Diet Aids — EatingToLive @ 5:36 pm

We all know that normal women who are not constantly being photographed and scrutinized are under a lot of pressure to be thin and look a certain way to fit a barbie doll image of sexiness and desirability, but women in Hollywood experience this same pressure tenfold, and the suspicion is that they may be succumbing to the use of a  particular dangerous drug to achieve this “super skinny” effect.

A drug called Clenbuterol may be behind some of the Hollywood dramatic size reductions these days, and it seems it is being used mostly by young women, with no regard to the fact that the drug is not even approved for human consumption, and has potentially life threatening effects.

What is Clenbuterol, and Why is This Underground Weight Loss Pill Potentially Dangerous?

Clenbuterol, or “Clen” as it is referred to sometimes, is actually a veterinary drug, approved mostly for use on horses with breathing problems.  It is known as a bronchodilator ths is essentially steroidal, but it’s side effects are as a long time thermogen, or fat burner, because it elevates resting heart rate and increases internal body temperature, and not the same as some healthier herbal weight loss pills, but at a very unnatural pace and not in a healthy way.

This is why it is known to quickly make people drop weight and burn off fat, because it increases the heart rate and the rate at which calories are burned, even when a person is not being physically active.

This is also why clenbuterol can have life threatening consequences.  When rats were tested that were given this drug meant for horses, hardening effect on the walls of the heart, which can lead to any number of heart problems and potentially even heart failure or irregular heart beats.

Clenbuterol is only legal for veterinary use in horses to treat breathing problems, and is not approved for human consumption (for a reason), yet a lot of individuals are buying this stuff over the internet with relative ease.

Logic would tell us that a drug powerful enough to treat a horse cannot be healthy for a much smaller human to consume, and yet it seems that thin-obsessed women are still putting their lives at risk in the name of being unnaturally thin to compete with the size zero next to them.

It gained notoriety inside certain circles when bodybuilders began using it to help them increase their muscle mass while simultaneously reducing their body fat at an unnaturally rapid rate.  In an short span of time, body builders were gaining significant amounts of muscle while reducing their body fat.

To put muscle on this quickly while also reducing body fat cannot be good for the heart, as it may put undue strain on it to keep up with the unnaturally high muscle content.  Muscles notoriously burn more calories than fat, and this puts the body into overdrive, forcing it to constantly burn it’s energy reserves (hence, the fast fat loss and size reduction).

Reported Long Term Effects of Clenbuterol : Not So Appealing to the Body Conscious

As with anything else that seems like it’s a “magic fix” in one area, Clenbuterol can has some extremely negative consequences to overall health and well being, and the side effects have not been studied on humans yet, so there is almost definitely more that we don’t even know about.

One side of this drug that may not be so appealing to the people who are taking it expressly to look rail thin is that those effects the drug was initially taken for may actually come back to bite you in the skinny rear end.  It almost sounds like the same case with the infamous fen-phen, or phentermine.

Apparently long term “Clen” users have experienced an unexplained ballooning of weight, presumably because the drug’s effect has worn off and the user’s body has become immune to it, and is trying to gain back the much needed fat that we are all genetically programmed to have (especially women).

Even if these long term users eat virtually nothing, or what would be considered a fairly restrictive diet, they have reported experiencing an uncontrollable surge in their weight.  So, it is quickly becoming apparent that clenbuterol is no magic bullet by any means, and unfortunately since it is not even approved for human consumption, studies are not really available as to the actual side effects of this potent drug. 

There may need to be some intervention by a government body to crack down on human usage, but we all know that if someone really wants something, it will most likely still be available on the black market for people.  As long as people realize they may be putting their health and very lives in serious jeopardy, there is really nothing more that can be done short of banning the sale of the drug and enforcing it strictly. 

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