Substance Called NAPE May Signal Fullness

A fatty substance or chemical was found in the stomach of lab mice in a recent study on a chemical found in the gut called NAPE.  NAPE’s role in fullness and appetite is believed to be that it carries a chemical signal to the brain, signaling to the brain that it is full and for the subject, hopefully humans as well share this same trait which they most likely do, so that they will stop eating. 

When researchers injected the chemical into the abdomen of the mice, they stopped eating much sooner, and over a time period they ended up losing weight when they were consistently dosed with NAPE.  Researchers are hoping that this discovery can lead to better prescription drugs for weight loss that help to reduce the appetite naturally a little better than what’s currently out there on the market for weight loss, since there aren’t too many very good and very effective options out there.

We do know that there is another way we can reduce the appetite and send these “full” signals to the brain much sooner, and that is by eating meals that are rich in omega 3 fatty acids. In the ZONE diet written by Dr. Barry Sears, he talks about how omega 3 fatty acids in your meals actually triggers something similar to where the brain is signaled much sooner than usual that the body is full, resulting in less food and calorie intake, which in turn results in- you guessed it – weight loss!